When obesity meds get blamed in the OR
A perioperative review argues that adverse effects from modern anti-obesity drugs can be mistaken for surgical or anesthesia complications, raising the bar for documentation, holds, and post-op restarts.
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View all newsA virus-mimicking peptide that pushes mRNA beyond the liver
Researchers describe an enveloped virus-mimicking particle built from a simplified peptide plus tuned lipids, aiming for repeatable mRNA delivery to extrahepatic tissues like lung and spleen.
Donkey-milk exosomes for oral octreotide
A new mouse study tests an exosome-based ‘biomimetic’ delivery idea for oral octreotide, hinting at a path beyond permeability enhancers but leaving big manufacturing and translation questions.
A dose-linked mental health signal for semaglutide
A large EHR-based preprint links semaglutide to lower rates of many neuropsychiatric diagnoses, with a ‘legacy’ signal that tracks maximum achieved dose more than weight loss.
GLP‑1 drugs and atrial fibrillation risk
A new observational study links GLP‑1 therapy to lower atrial fibrillation risk even when people do not lose weight, with the strongest signal reported for semaglutide.
GLP‑1 plus SGLT2 in fatty liver disease
A large real-world analysis links GLP‑1 plus SGLT2 combination therapy to lower rates of major liver and cardiovascular events in people with fatty liver disease and type 2 diabetes.
How vosoritide looks after one year
A new meta-analysis pools one-year results for vosoritide in children with achondroplasia, clarifying typical growth changes and the most common side effects.
Rosuvastatin may briefly blunt post-meal GLP‑1
A translational study links cholesterol-pathway inhibition (HMGCR/rosuvastatin) to lower acute GLP‑1 secretion in gut cells and mice, offering a plausible mechanism behind statins’ mild diabetes signal.
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Ac2-26BPC-157CJC-1295CYP9DermcidinDOTATATEELABELAEpitalonGHK-CuGlucagon-like peptide-1 (GLP-1)GonadorelinHDAP2
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NewsMetabolic healthClinicalGLP-1SafetyDiabetesInfectious diseasemethodsObesityImmuneNeuroscienceBPC-157
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