HNP1
HNP1 (human neutrophil peptide 1) is an alpha-defensin antimicrobial peptide produced by neutrophils and studied for membrane-active antibacterial effects and synergy with other innate peptides.
Tag
Immune
Pages related to Immune.
LL-37
LL-37 (cathelicidin) is a human antimicrobial peptide involved in innate immune defense and widely studied for membrane-active antibacterial and immunomodulatory effects.
Vasoactive intestinal peptide (VIP)
Vasoactive intestinal peptide (VIP) is an endogenous neuropeptide hormone involved in vasodilation, smooth muscle relaxation, and immune signaling. A 2026 preclinical paper reported VIP-induced autophagy and cytotoxicity in renal cell carcinoma models via a proposed SIRT3-dependent pathway.
Dermcidin
Dermcidin is a human antimicrobial peptide found in sweat and other tissues. A 2026 study reported antiviral activity against influenza via binding hemagglutinin, with mouse protection data.
Thymosin Alpha-1
An immune-modulating peptide (thymalfasin) studied across infectious and immune contexts.
Two immune peptides team up against bacteria
A new mechanistic study suggests LL-37 and HNP1 can form reversible aggregates that become more active on bacterial-like membranes while staying less toxic to human cells.
A human skin peptide that blocks influenza
A PNAS study reports that dermcidin, an antimicrobial peptide found in sweat, can bind influenza hemagglutinin, inhibit infection in vitro, and protect mice, with higher levels seen in asymptomatic humans.