HDAP2
A mitochondria-targeted aromatic peptide investigated in preclinical models of axonal injury and retinal ganglion cell neuroprotection.
Tag
Neuroscience
Pages related to Neuroscience.
Pinealon
A short peptide (often discussed as an EDR peptide family) that appears in gerontology and neurobiology literature; widely marketed online for sleep and brain benefits with limited modern clinical evidence.
Hi1a
A disulfide-rich venom peptide from the Australian funnel-web spider that is being investigated for neuroprotection in ischemic stroke, with challenging manufacturing and folding requirements.
Amylin may shape anxiety and sociability, differently by sex
A rat study links the pancreatic hormone amylin to anxiety-like behavior, aggression, and sociability, with the central amygdala driving some effects in opposite directions in males and females.
A neural clue for GLP-1 drugs’ heart rate bump
In an in vitro rat brainstem-spinal cord setup, exendin-4 increased sympathetic nerve activity and depolarized key neurons, supporting a direct neural route for GLP-1 receptor agonist tachycardia.
A mitochondria-targeted peptide for optic nerve injury
In a mouse optic nerve crush model, the research peptide HDAP2 was associated with less mitochondrial loss in injured axons and higher retinal ganglion cell survival. Early preclinical neuroprotection, not a human result.
Hi1a is still hard science—but it just got easier to make
A new paper reports a rapid ‘single-shot’ automated method to chemically synthesize linear Hi1a, a disulfide-rich venom peptide studied for neuroprotection. It’s not a clinical result, but it can remove a real bottleneck.