LEAP2
Liver-expressed antimicrobial peptide 2 (LEAP2) is an endogenous peptide that antagonizes ghrelin receptor signaling and has been studied in humans for acute effects on appetite and post-meal glucose.
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Liver-expressed antimicrobial peptide 2 (LEAP2) is an endogenous peptide that antagonizes ghrelin receptor signaling and has been studied in humans for acute effects on appetite and post-meal glucose.
A mitochondria-targeted aromatic peptide investigated in preclinical models of axonal injury and retinal ganglion cell neuroprotection.
A cyclic peptide engineered from an antimicrobial peptide scaffold (YD) that showed preclinical anti-fibrotic activity by suppressing TGF-β/Smad and MAPK pathway signaling in experimental models.
A disulfide-rich venom peptide from the Australian funnel-web spider that is being investigated for neuroprotection in ischemic stroke, with challenging manufacturing and folding requirements.
A research-stage recovery peptide discussed for soft tissue healing and gut protection.
A mitochondrial-derived peptide discussed for metabolic resilience and exercise-adjacent effects.