Lyngbyabellin Q
A marine cyanobacterial cyclic peptide natural product reported to disrupt actin dynamics and show potent in vitro antimalarial activity.
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A marine cyanobacterial cyclic peptide natural product reported to disrupt actin dynamics and show potent in vitro antimalarial activity.
Lyngbyabellin Q, a marine cyanobacterial cyclic peptide, showed potent in vitro antimalarial activity but also signals actin-related cytotoxicity. A classic ‘potent but sharp’ natural-products starting point.