HDAP2
A mitochondria-targeted aromatic peptide investigated in preclinical models of axonal injury and retinal ganglion cell neuroprotection.
Tag
Mitochondria
Pages related to Mitochondria.
MOTS-c
A mitochondrial-derived peptide discussed for metabolic resilience and exercise-adjacent effects.
A pregnancy peptide tied to fetal heart defects
A study in humans and mice links lower ELABELA (ELA) levels to congenital heart disease and suggests a mitochondria-related mechanism in cardiac development. Promising as a biomarker lead, not a clinical test yet.
A mitochondria-targeted peptide for optic nerve injury
In a mouse optic nerve crush model, the research peptide HDAP2 was associated with less mitochondrial loss in injured axons and higher retinal ganglion cell survival. Early preclinical neuroprotection, not a human result.
MOTS‑c isn’t a weight-loss switch. It’s a mitochondria signal
MOTS‑c is a real mitochondrial DNA-encoded peptide with intriguing metabolic effects in animal studies, but human evidence is still early and easy to overhype.