Mental Health

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Pages related to Mental Health.

A dose-linked mental health signal for semaglutide

A large EHR-based preprint links semaglutide to lower rates of many neuropsychiatric diagnoses, with a ‘legacy’ signal that tracks maximum achieved dose more than weight loss.

news April 24, 2026

GLP-1 drugs and depression: a meta-analysis finds a signal, but the heterogeneity is huge

An open-access meta-analysis reports higher odds of depression-related adverse events among GLP-1 receptor agonist users (OR 1.49), but between-study heterogeneity is extreme (I² ~99%), which limits how literally the pooled number should be taken.

news March 28, 2026