Lachnospirin-1
A novel antimicrobial peptide reported in 2026 to have activity against carbapenem-resistant Acinetobacter baumannii in vitro and in mouse infection models.
Tag
Antimicrobial
Antimicrobial peptides are a long-running idea for new antibiotics. This tag tracks real research progress, plus the translation problems that keep recurring.
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Two immune peptides team up against bacteria
A new mechanistic study suggests LL-37 and HNP1 can form reversible aggregates that become more active on bacterial-like membranes while staying less toxic to human cells.
Why CRAB still needs new antibiotics: lachnospirin‑1 as an early lead
A 2026 *Virulence* paper reports that lachnospirin‑1 killed carbapenem-resistant *A. baumannii*, disrupted biofilms and persisters, and showed efficacy in mouse infection models. It is still preclinical, but it has the kind of signal package that can justify deeper development.