Anti-fibrotic

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CYP9

A cyclic peptide engineered from an antimicrobial peptide scaffold (YD) that showed preclinical anti-fibrotic activity by suppressing TGF-β/Smad and MAPK pathway signaling in experimental models.

peptides March 25, 2026

A cyclic peptide shows antifibrotic promise in mice

Researchers took an antimicrobial peptide, tightened it into a drug-like cyclic version (CYP9), and reported reduced lung-fibrosis signaling in preclinical models. Early, but a useful example of peptide engineering.

news March 25, 2026